By Lynn M. Schnapp, Carol Feghali-Bostwick
Acute respiration misery Syndrome (ARDS) is still an immense reason behind morbidity and mortality around the world, and the occurrence is expected to extend with the getting older inhabitants a number of medical issues can start up ARDS, together with pneumonia, sepsis, gastric aspiration and trauma yet regardless of severe learn during the last forty years, we nonetheless have an incomplete knowing of the pathophysiology of the ailment and remedy is still principally supportive. This e-book offers an summary of acute lung harm and service, describes present animal types to review lung harm and reports present methodologies to review and degree lung harm and service. precise emphasis is given to state-of-the-art recommendations and strategies and relevance to human illness. Acute Lung harm and service: clinical basics and strategies is an invaluable source for physicians and scientists who're attracted to experimental version structures for perception into ARDS pathogenesis and therapy options.
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Extra resources for Acute Lung Injury and Repair: Scientific Fundamentals and Methods
J Mol Biol. 1999;285(1):175–82. 23. Minamino T, Gaussin V, DeMayo FJ, Schneider MD. Inducible gene targeting in postnatal myocardium by cardiac-speciﬁc expression of a hormone-activated Cre fusion protein. Circ Res. 2001;88(6):587–92. 24. Sando R 3rd, Baumgaertel K, Pieraut S, Torabi-Rander N, Wandless TJ, Mayford M, Maximov A. Inducible control of gene expression with destabilized Cre. Nat Methods. 2013;10(11):1085–8. 25. Okubo T, Knoepfler PS, Eisenman RN, Hogan BL. Nmyc plays an essential role during lung development as a dosage-sensitive regulator of progenitor cell proliferation and differentiation.
2006;10:R136. 1186/cc5050. 2 Mouse Models of Acute Lung Injury 23 49. Gharib SA, Liles WC, Matute-Bello G, Glenny RW, Martin TR, Altemeier WA. Computational identiﬁcation of key biological modules and transcription factors in acute lung injury. Am J Respir Crit Care Med. 2006;173:653–8. 200509-1473OC. 50. Gharib SA, Liles WC, Klaff LS, Altemeier WA. Noninjurious mechanical ventilation activates a proinflammatory transcriptional program in the lung. Physiol Genomics. 2009;37:239–48. 2009. 51. Bomsztyk K, Mar D, An D, Shariﬁan R, Mikula M, Gharib SA, et al.
Antimicrob Agents Chemother. 1965;5:1079–85. 41. Gasse P, Mary C, Guenon I, Noulin N, Charron S, Schnyder-Candrian S, et al. IL-1R1/MyD88 signaling and the inflammasome are essential in pulmonary inflammation and ﬁbrosis in mice. J Clin Invest. 2007;117:3786–99. 1172/JCI32285. 42. Xu J, Mora A, Shim H, Stecenko A, Brigham KL, Rojas M. Role of the SDF-1/CXCR4 axis in the pathogenesis of lung injury and ﬁbrosis. Am J Respir Cell Mol Biol. 2007;37:291–9. 2006-0187OC. 43. Bundesmann MM, Wagner TE, Chow Y-H, Altemeier WA, Steinbach T, Schnapp LM.